University of Wisconsin
School of Medicine and Public Health



Neuroimaging research is focused on presymptomatic detection of disease through MRI and PET imaging and identifying biological and lifestyle factors that confer risk and resilience in Alzheimer’s disease and related dementias. The study of factors that contribute to health or pathological brain aging include the impact of mid-life metabolic effect of mid-life metabolic disorders (obesity and insulin resistance), sleep, diet, and microbial influences. Expanded research also focuses on clinical psychopharmacology and neuroendocrinology of gonadal steroids and cholinergic drugs in Alzheimer’s disease and healthy aging through clinical trials that using neuroimaging and biofluid biomarkers to examine the potential effects of hormones on Alzheimer’s disease pathobiology.