University of Wisconsin
School of Medicine and Public Health

Betthauser Research

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Dr Tobey Betthauser

Tobey Betthauser, PhD: The Time Course of Alzheimer’s Disease and Related Disorders

Tobey Betthauser, PhD, leads research to better understand the sequence of events that occur in neurodegenerative diseases, with a focus on Alzheimer’s disease.

Dr. Tobey Betthauser's Faculty Profile

Biomarkers for AD Detection and Progression

In Alzheimer’s disease, characteristic pathologic lesions form one to two decades prior to the onset of cognitive symptoms, during a phase referred to as “preclinical AD.” Dr. Betthauser’s current work includes developing and evaluating novel approaches to characterizing the time course of amyloid accumulation and other pathophysiologic processes in AD using biomarkers for these biological targets.

Dr. Betthauser's team also investigates the sensitivity and specificity of in vivo biomarkers for their molecular targets with postmortem confirmation of pathologic entities.

This combined research is designed to better the understanding of the clinical and research utility and limitations of fluid and imaging biomarkers to detect pathophysiologic processes during life, and to better understand how these pathologic processes influence symptoms of disease.

Active Projects

  • Longitudinal biomarker modeling
  • Neuropathological validation of in vivo biomarker

Publications

View Dr. Tobey Betthauser's publications on NCBI MyBibliography.