University of Wisconsin
School of Medicine and Public Health

Clinical Research

To find additional clinical research studies that involve a treatment or intervention for adults and older adults, please visit the Aging & Geriatrics section of the UW Health StudyFinder website

Studies for adults and older adults not listed on that site appear below.

Alzheimer's Disease Resiliency

ADRC Clinical Core Study

People who join the Clinical Core attend a yearly or every other year visit with a study partner. Study procedures include memory and thinking ability evaluations, physical examination, blood collection, lumbar puncture, and brain scans. They also agree to be contacted about other ADRC-affiliated studies.

Population and age group: People with Alzheimer's disease, people with mild cognitive impairment (MCI), People age 45-65 with or without a parental history of AD.

PrincipaI Investigator: Sanjay Asthana, MD

Contact: Bonnie Nuttkinson

ARMADA

The ARMADA study investigates a new set of measures on the iPad to determine if they can detect early signs of cognitive decline. This study involves tests of thinking abilities, emotions, and sensory and motor functions.

Population and age group: Individuals with a diagnosis of Alzheimer's Disease or African Americans with Mild Cognitive Impairment, who are 65 years old or older. 

PrincipaI Investigator: Cindy Carlsson, MD

Contact: Colleen Mellert 

BRAVE

The observational arm of the A4 study. The study involves six in-person visits spread over 18 months at the William S. Middleton Memorial Veterans Hospital.

Population and age group: VA-eligible Veterans aged 50-75 years without a diagnosis of a memory disorder. 

PrincipaI Investigator: Cindy Carlsson, MD

Contact:

Health Services Research

Building Bridges Project

Building Bridges is a community outreach project assessing an individual’s willingness to participate in research studies and trust in medical researchers based on two different community events. Our ultimate goal is to develop alternative recruitment strategies to increase racial/ethnic minority group participation in our dementia studies as well as increasing dementia awareness.

Population and age group: Black/African American participants age 45 and above

PrincipaI Investigator: Shenikqua Bouges, MD

Contact: Shenikqua Bouges, MD

A Randomized, Open-Label, Phase 2 Study of Abaloparatide to Mitigate Distal Femoral Bone Loss Following Total Knee Arthroplasty

This study will assess whether a medication called abaloparatide will reduce the amount of bone lost after a total knee replacement surgery.

Population and age group: Those who plan to have knee replacement surgery age ≥ 55 years.

PrincipaI Investigator: Neil Binkley, MD

Contact: Osteoporosis Clinical Research Program, 608-265-6410

Neuroimaging

The Synapse Project

The purpose of this study is to collect brain scans and determine if synapse density is related to Alzheimer’s pathology.

Population and age group: Eligible participants from the Wisconsin Alzheimer’s Disease Research Center Clinical Core, WRAP Study and the UW Memory Clinic can participate in this study.

Principal Investigator: Barbara Bendlin, PhD

Contact: Mary Elizabeth Pasquesi