University of Wisconsin
School of Medicine and Public Health

Statistical Data Analysis Center (SDAC)

The SDAC is an integral part of the Department of Biostatistics and Medical Informatics. SDAC is designed to:

  • support UW investigators conducting cutting-edge research through multicenter clinical trials
  • promote statistical practice, applications and research in preparing Data Monitoring Committee reports necessary to evaluate the accumulating evidence for safety and efficacy
  • act as a research and demonstration project for educating students and investigators in analyzing and processing data collected in multicenter clinical trials

SDAC is expert in designing, conducting and analyzing clinical trials, especially in the areas of cardiology, neurology and oncology. SDAC staff have extensive clinical research experience, including multicenter studies of therapeutic and preventive cardiac interventions. They collaborate in developing protocols, including study design, sample size calculations, final analysis plan and interim data monitoring. They also help investigators formulate the data collection process, including design of case report forms.

Before performing planned analyses, SDAC helps explore many aspects of data analysis, such as relationships among variables and implications of missing data. The current SDAC research portfolio includes serving as the independent Data Analysis Center for 11 multicenter clinical trials involving approximately 20,000 patients. Examples of cardiac trials include MERIT, PRAISE-2, COPERNICUS, VEST, REACH, EXCITE, CARS, WIZARD and ENABLE.


Contact Information

David L. DeMets, PhD
K6/446 CSC
600 Highland Avenue
Madison, WI 53792
Phone: (608) 263-2947
Fax: (608) 263-1059
Email: demets@biostat.wisc.edu
Link: https://ictr.wisc.edu/groups/office-of-clinical-trials-oct/