Recent Publications

November

• Li H, Sun CY, Fang Y, Carlson CM, Xu H, Ješovnik A, Sosa-Calvo J, Zarnowski R, Bechtel HA, Fournelle JH, Andes DR, Schultz TR, Gilbert P, Currie CR. Biomineral armor in leaf-cutter ants. Nat Commun. 2020;11(1):5792.
• Zhang F, Zhao M, Braun DR, Ericksen SS, Piotrowski JS, Nelson J, Peng J, Ananiev GE, Chanana S, Barns K, Fossen J, Sanchez H, Chevrette MG, Guzei IA, Zhao C, Guo L, Tang W, Currie CR, Rajski SR, Audhya A, Andes DR, Bugni TS. A marine microbiome antifungal targets urgent-threat drug-resistant fungi. Science. 2020;370(6519):974-978.
• Hammond EN, Brys N, Kates A, Musuuza JS, Haleem A, Bentz ML, Safdar N. Nasal povidone-iodine implementation for preventing surgical site infections: Perspectives of surgical nurses. PLoS One. 2020;15(11):e0242217.
• Pulia MS, Wolf I, Schwei RJ, Chen D, Lepak AJ, Schulz LT, Safdar N. Antibiotic Prescribing Patterns for COVD-19 in Two Emergency Departments with Rapid Procalcitonin. Infect Control Hosp Epidemiol. 2020:1-7.
• Zwick ED, Pepperell CS. Tuberculosis sanatorium treatment at the advent of the chemotherapy era. BMC Infect Dis. 2020;20(1):831.
• Neidlinger NA, Smith JA, D'Alessandro AM, Roe D, Taber TE, Pereira MR, Friedman AL. Organ recovery from deceased donors with prior COVID-19: a case series. Transpl Infect Dis. 2020:e13503.

October

• Vanamala K, Tatiparti K, Bhise K, Sau S, Scheetz MH, Rybak MJ, Andes D, Iyer AK. Novel approaches for the treatment of methicillin-resistant Staphylococcus aureus: Using nanoparticles to overcome multidrug resistance. Drug Discov Today. 2020.
• Byrne JM, Waack U, Weinstein EA, Joshi A, Shurland SM, Iarikov D, Bulitta JB, Diep BA, Guina T, Hope WW, Lawrenz MB, Lepak AJ, Luna BM, Miesel L, Phipps AJ, Walsh TJ, Weiss W, Amini T, Farley JJ. FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development. Antimicrob Agents Chemother. 2020.
• Lepak AJ, Shirley DK, Buys A, Stevens L, Safdar N. Implementation of infection control measures to prevent healthcare-associated transmission of severe acute respiratory coronavirus virus 2 (SARS-CoV-2). Infect Control Hosp Epidemiol. 2020:1-4.
• Alter SM, Maki DG, LeBlang S, Shih RD, Hennekens CH. The menacing assaults on science, FDA, CDC, and health of the US public. EClinicalMedicine. 2020;27:100581.
• Shih RD, Maki DG, Hennekens CH. Remdesivir for coronavirus 2019 (COVID-19): More promising but still unproven. Contemp Clin Trials Commun. 2020;20:100663.
• McBride JA, Eickhoff J, Wald ER. IMPACT OF COVID-19 QUARANTINE AND SCHOOL CANCELATION ON OTHER COMMON INFECTIOUS DISEASES. Pediatr Infect Dis J. 2020.
• Wolday D, Legesse D, Kebede Y, Siraj DS, McBride JA, Striker R. Immune recovery in HIV-1 infected patients with sustained viral suppression under long-term antiretroviral therapy in Ethiopia. PLoS One. 2020;15(10):e0240880.
• Moreno GK, Braun KM, Riemersma KK, Martin MA, Halfmann PJ, Crooks CM, Prall T, Baker D, Baczenas JJ, Heffron AS, Ramuta M, Khubbar M, Weiler AM, Accola MA, Rehrauer WM, O'Connor SL, Safdar N, Pepperell CS, Dasu T, Bhattacharyya S, Kawaoka Y, Koelle K, O'Connor DH, Friedrich TC. Revealing fine-scale spatiotemporal differences in SARS-CoV-2 introduction and spread. Nat Commun. 2020;11(1):5558.
• Alagoz O, Sethi AK, Patterson BW, Churpek M, Safdar N. Effect of Timing of and Adherence to Social Distancing Measures on COVID-19 Burden in the United States : A Simulation Modeling Approach. Ann Intern Med. 2020.
• Keating JA, McKinley L, Safdar N. Coronavirus disease 2019 (COVID-19) and antibiotic stewardship: Using a systems engineering approach to maintain patient safety. Infect Control Hosp Epidemiol. 2020:1-3.
• Scaria E, Powell WR, Birstler J, Alagoz O, Shirley D, Kind AJH, Safdar N. Neighborhood disadvantage and 30-day readmission risk following Clostridioides difficile infection hospitalization. BMC Infect Dis. 2020;20(1):762.
• Jorgenson MR, Gracon AS, Hanlon B, Leverson GE, Parajuli S, Smith JA, Al-Adra DP. Pre-transplant bariatric surgery is associated with increased fungal infection after liver transplant. Transpl Infect Dis. 2020:e13484.
• Geltzeiler CB, Xu Y, Carchman E, Ghouse Y, Beczkiewicz J, Son J, Voils CI, Striker R. CD4/CD8 Ratio as a Novel Marker for Increased Risk of High-Grade Anal Dysplasia and Anal Cancer in HIV+ Patients: A Retrospective Cohort Study. Dis Colon Rectum. 2020;63(12):1585-1592.
• Hochstatter KR, Hull SJ, Sethi AK, Burns ME, Mundt MP, Westergaard RP. Promoting Safe Injection Practices, Substance Use Reduction, Hepatitis C Testing, and Overdose Prevention Among Syringe Service Program Clients Using a Computer-Tailored Intervention: Pilot Randomized Controlled Trial. J Med Internet Res. 2020;22(9):e19703.

September

• Lepak AJ, Wang W, Andes DR. Pharmacodynamic Evaluation of MRX-8, a Novel Polymyxin, in the Neutropenic Mouse Thigh and Lung Infection Models Against Gram-Negative Pathogens. Antimicrob Agents Chemother. 2020.
• Hanlon JT, Perera S, Schweon S, Drinka P, Crnich C, Nace DA. Improvements in Antibiotic Appropriateness for Cystitis in Older Nursing Home Residents: A Quality Improvement Study With Randomized Assignment. J Am Med Dir Assoc. 2020.
• Lepak AJ, Chen DJ, Buys A, Stevens L, Safdar N. Utility of Repeat Nasopharyngeal SARS-CoV-2 RT-PCR Testing and Refinement of Diagnostic Stewardship Strategies at a Tertiary Care Academic Center in a Low-Prevalence Area of the United States. Open Forum Infect Dis. 2020;7(9):ofaa388.
• Pulia MS, Wolf I, Schulz LT, Pop-Vicas A, Schwei RJ, Lindenauer PK. COVID-19: An Emerging Threat to Antibiotic Stewardship in the Emergency Department. In: West J Emerg Med. Vol 21. United States2020:1283-1286.
• Ramanathan S, Suda KJ, Fitzpatrick MA, Guihan M, Goedken CC, Safdar N, Evans M, Jones M, Pfeiffer CD, Perencevich EN, Rubin M, Evans CT. A survey of infection control strategies for carbapenem-resistant Enterobacteriaceae in Department of Veterans' Affairs facilities. Infect Control Hosp Epidemiol. 2020:1-4.
• Siraj A, Worku A, Berhane K, Aregawi M, Eshetu M, Mirkuzie A, Berhane Y, Siraj D. Early estimates of COVID-19 infections in small, medium and large population clusters. BMJ Glob Health. 2020;5(9).
• Motzer RJ, Jonasch E, Boyle S, Carlo MI, Manley B, Agarwal N, Alva A, Beckermann K, Choueiri TK, Costello BA, Derweesh IH, Desai A, George S, Gore JL, Haas N, Hancock SL, Kyriakopoulos C, Lam ET, Lau C, Lewis B, Madoff DC, McCreery B, Michaelson MD, Mortazavi A, Nandagopal L, Pierorazio PM, Plimack ER, Ponsky L, Ramalingam S, Shuch B, Smith ZL, Somer B, Sosman J, Dwyer MA, Motter AD. NCCN Guidelines Insights: Kidney Cancer, Version 1.2021. J Natl Compr Canc Netw. 2020;18(9):1160-1170. 

August

• Barker AK, Scaria E, Safdar N, Alagoz O. Evaluation of the Cost-effectiveness of Infection Control Strategies to Reduce Hospital-Onset Clostridioides difficile Infection. JAMA Netw Open. 2020;3(8):e2012522.
• Johnson MD, Lewis RE, Dodds Ashley ES, Ostrosky-Zeichner L, Zaoutis T, Thompson GR, Andes DR, Walsh TJ, Pappas PG, Cornely OA, Perfect JR, Kontoyiannis DP. Core Recommendations for Antifungal Stewardship: A Statement of the Mycoses Study Group Education and Research Consortium. J Infect Dis. 2020;222(Supplement_3):S175-s198.
• Tischendorf J, Brunner M, Knobloch MJ, Schulz L, Barker A, Wright MO, Lepak A, Safdar N. Evaluation of a successful fluoroquinolone restriction intervention among high-risk patients: A mixed-methods study. PLoS One. 2020;15(8):e0237987.
• Solano JJ, Maki DG, Adirim TA, Shih RD, Hennekens CH. Public Health Strategies Contain and Mitigate COVID-19: A Tale of Two Democracies. Am J Med. 2020.
• Rush TA, Puech-PagËs V, Bascaules A, Jargeat P, Maillet F, Haouy A, MaÎs AQ, Carriel CC, Khokhani D, Keller-Pearson M, Tannous J, Cope KR, Garcia K, Maeda J, Johnson C, Kleven B, Choudhury QJ, LabbÈ J, Swift C, O'Malley MA, Bok JW, Cottaz S, Fort S, Poinsot V, Sussman MR, Lefort C, Nett J, Keller NP, BÈcard G, AnÈ JM. Lipo-chitooligosaccharides as regulatory signals of fungal growth and development. Nat Commun. 2020;11(1):3897.
• Eggers S, Gennings C, Malecki KMC, Safdar N, Arora M. Exposure to environmental chemical mixtures is associated with nasal colonization by Staphylococcus aureus: NHANES 2001-2004. Environ Res. 2020;190:109994.
• Rivera F, Safdar N, Ledeboer N, Schaack G, Chen DJ, Munoz-Price LS. Prevalence of SARS-CoV-2 asymptomatic infections in two large academic health systems in Wisconsin. Clin Infect Dis. 2020.

July

• Hochstatter KR, Akhtar WZ, Dietz S, Pe-Romashko K, Gustafson DH, Shah DV, Krechel S, Liebert C, Miller R, El-Bassel N, Westergaard RP. Potential Influences of the COVID-19 Pandemic on Drug Use and HIV Care Among People Living with HIV and Substance Use Disorders: Experience from a Pilot mHealth Intervention. AIDS Behav. 2020:1-6.
• McCreary EK, Nguyen MH, Davis MR, Borlagdan J, Shields RK, Anderson AD, Rivosecchi RM, Marini RV, Sacha LM, Silveira FP, Andes DR, Lepak AJ. Achievement of clinical isavuconazole blood concentrations in transplant recipients with isavuconazonium sulphate capsules administered via enteral feeding tube. J Antimicrob Chemother. 2020.
• Ramly E, Tong M, Bondar S, Ford JH, 2nd, Nace DA, Crnich CJ. Workflow Barriers and Strategies to Reduce Antibiotic Overuse in Nursing Homes. J Am Geriatr Soc. 2020.
• Taylor L, Condon T, Destrampe EM, et al. Powassan Virus Infection Likely Acquired Through Blood Transfusion Presenting as Encephalitis in a Kidney Transplant Recipient. Clinical Infectious Diseases. 2020. 

June 

• Kates AE, Gaulke I, De Wolfe T, Zimbric M, Haight K, Watson L, Suen G, Kim K, Safdar N. Fecal microbiota transplantation for patients on antibiotic treatment with C. difficile infection history (GRAFT): Study protocol for a phase II, randomized, double-blind, placebo-controlled trial to prevent recurrent C. difficile infections. Contemp Clin Trials Commun. 2020;18:100576.
• Kessler MA, Joachim EL, Narayanan D, Medani S, Urban AW, Parajuli S. On the tip of my tongue: A 76-year-old female kidney transplant patient with tongue ulcer. Transpl Infect Dis. 2020:e13389.
• Laux KL, Anderson JL, Bentivenga SP, McBride JA, Sterkel A, Matkovic E, Gauthier GM, Meece JK. Urine Antigen Testing is Equally Sensitive to B. dermatitidis and B. gilchristii Infections. Clin Med Res. 2020.
• Malecki K, Keating JA, Safdar N. Crisis Communication and Public Perception of COVID-19 Risk in the Era of Social Media. Clin Infect Dis. 2020.
• Sutherland BL, Pecanac K, Bartels CM, Brennan MB. Expect delays: poor connections between rural and urban health systems challenge multidisciplinary care for rural Americans with diabetic foot ulcers. J Foot Ankle Res. 2020;13(1):32.
• Taylor L, Stevens T, Destrampe EM, Brown JA, McGavic J, Gould CV, Chambers TV, Kosoy OI, Burkhalter KL, Annambhotla P, Basavaraju SV, Groves J, Osborn RA, Weiss J, Stramer SL, Misch EA. Powassan virus infection likely acquired through blood transfusion presenting as encephalitis in a kidney transplant recipient. Clin Infect Dis. 2020.

May

• Aziz F, Saddler C, Jorgenson M, Smith J, Mandelbrot D. Epidemiology, management, and graft outcomes after West Nile virus encephalitis in kidney transplant recipients. Transpl Infect Dis. 2020:e13317.
• Brunner M, Vogelman B, Smith J. Rapid Development of an Outpatient-To-Inpatient Crash Curriculum for COVID Providers. Med Educ. 2020. 
• Jorgenson MR, Descourouez JL, Schulz LT, Goldrosen KA, Rice JP, Redfield RR, Saddler CM, Smith JA, Mandelbrot DA. The development and implementation of stewardship initiatives to optimize the prevention and treatment of cytomegalovirus infection in solid-organ transplant recipients. Infect Control Hosp Epidemiol. 2020:1-7.
• Jorgenson MR, Hillis MI, Saddler CM, Smith JA, Parajuli S, Mandelbrot DA. Prediction of cytomegalovirus infection: A single-center experience utilizing a newly available cell-mediated immunity assay by flow cytometry, a risk factor screening tool, and serologically demonstrated immunity. Transpl Infect Dis. 2020:e13311.
• Nace DA, Hanlon JT, Crnich CJ, Drinka PJ, Schweon SJ, Anderson G, Perera S. A Multifaceted Antimicrobial Stewardship Program for the Treatment of Uncomplicated Cystitis in Nursing Home Residents. JAMA Intern Med. 2020. 
• Pop-Vicas AE, Abad C, Baubie K, Osman F, Heise C, Safdar N. Colorectal bundles for surgical site infection prevention: A systematic review and meta-analysis. Infect Control Hosp Epidemiol. 2020:1-8.
• Shih RD, Johnson HM, Maki DG, Hennekens CH. Hydroxychloroquine for Coronavirus: The Urgent Need for a Moratorium on Prescriptions. Am J Med. 2020. 
• Thomas CS, Braun DR, Olmos JL, Jr., Rajski SR, Phillips GN, Jr., Andes D, Bugni TS. Pyridine-2,6-Dithiocarboxylic Acid and Its Metal Complexes: New Inhibitors of New Delhi Metallo β-Lactamase-1. Mar Drugs. 2020;18(6). 

April

• Beredaki MI, Georgiou PC, Siopi M, Kanioura L, Andes D, Arendrup MC, Mouton JW, Meletiadis J. Towards harmonization of voriconazole CLSI and EUCAST breakpoints for Candida albicans using a validated in vitro pharmacokinetic/pharmacodynamic model. Antimicrob Agents Chemother. 2020.
• Jasper AS, Musuuza JS, Tischendorf JS, Stevens VW, Gamage SD, Osman F, Safdar N. Are Fluoroquinolones or Macrolides Better for Treating Legionella Pneumonia? A Systematic Review and Meta-analysis. Clin Infect Dis. 2020.
• Musuuza JS, Roberts TJ, Hundt AS, Carayon P, Zimbric ML, Schuetz V, Reppen M, Smith W, Koffarnus K, Brown RL, Bowling J, Jalali K, Safdar N. Implementing daily chlorhexidine gluconate treatment for the prevention of healthcare-associated infections in non-intensive care settings: A multiple case analysis. PLoS One. 2020;15(4):e0232062.

March

• Abad CL, Barker AK, Safdar N. A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associated C. difficile and multidrug-resistant organisms. Infect Control Hosp Epidemiol. 2020:1-19.
• Akhtar WZ, Mundt MP, Koepke R, Krechel S, Fiore MC, Seal DW, Westergaard RP. Prevalence of Tobacco Use Among Rural-Dwelling Individuals Who Inject Drugs. JAMA Netw Open. 2020;3(3):e200493.
• Hennekens CH, George S, Adirim TA, Johnson H, Maki DG. The Emerging Pandemic of Coronavirus: The Urgent Need for Public Health Leadership. Am J Med. 2020.
• Kates AE, Jarrett O, Skarlupka JH, Sethi A, Duster M, Watson L, Suen G, Poulsen K, Safdar N. Household Pet Ownership and the Microbial Diversity of the Human Gut Microbiota. Front Cell Infect Microbiol. 2020;10:73.
• McBride JA, Sterkel AK, Matkovic E, Broman AT, Gibbons-Burgener SN, Gauthier GM. Clinical Manifestations and Outcomes in Immunocompetent and Immunocompromised Patients with Blastomycosis. Clin Infect Dis. 2020.
• Merkhofer RM, Klein BS. Advances in Understanding Human Genetic Variations That Influence Innate Immunity to Fungi. Front Cell Infect Microbiol. 2020;10:69.
• Wiesner DL, Merkhofer RM, Ober C, Kujoth GC, Niu M, Keller NP, Gern JE, Brockman-Schneider RA, Evans MD, Jackson DJ, Warner T, Jarjour NN, Esnault SJ, Feldman MB, Freeman M, Mou H, Vyas JM, Klein BS. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe. 2020.

February 

• Ai A, Anderson L, Safdar N, Shirley D. Barriers and facilitators to standardization of ultrasound use and probe disinfection in the ambulatory setting. Infect Control Hosp Epidemiol. 2020:1-3. 
• Barker AK, Scaria E, Alagoz O, Sethi AK, Safdar N. Reducing C. difficile in children: An agent-based modeling approach to evaluate intervention effectiveness. Infect Control Hosp Epidemiol. 2020:1-9. 
• Brunner MC, Sheehan SE, Yanke EM, Sittig DF, Safdar N, Hill B, Lee KS, Orwin JF, Vanness DJ, Hildebrand CJ, Bruno MA, Erickson TJ, Zea R, Moberg DP. Joint Design with Providers of Clinical Decision Support for Value-Based Advanced Shoulder Imaging. Appl Clin Inform. 2020;11(1):142-152. 
• Nett JE, Andes DR. Contributions of the Biofilm Matrix to Candida Pathogenesis. J Fungi (Basel). 2020;6(1). 
• Romero-Masters JC, Huebner SM, Ohashi M, Bristol JA, Benner BE, Barlow EA, Turk GL, Nelson SE, Baiu DC, Van Sciver N, Ranheim EA, Gumperz J, Sherer NM, Farrell PJ, Johannsen EC, Kenney SC. B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection. PLoS Pathog. 2020;16(2):e1008365.

January

• Horton MV, Johnson CJ, Kernien JF, Patel TD, Lam BC, Cheong JZA, Meudt JJ, Shanmuganayagam D, Kalan LR, Nett JE. Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin.mSphere. 2020;5(1).
• Mulholland CV, Shockey AC, Aung HL, Cursons RT, O'Toole RF, Gautam SS, Brites D, Gagneux S, Roberts SA, Karalus N, Cook GM, Pepperell CS, Arcus VL. Dispersal of Mycobacterium tuberculosis Driven by Historical European Trade in the South Pacific. Front Microbiol. 2019;10:2778. 
• Sheehan SE, Safdar N, Singh H, Sittig DF, Bruno MA, Keller K, Kinnard S, Brunner MC. Detection and Remediation of Misidentification Errors in Radiology Examination Ordering. Appl Clin Inform. 2020;11(1):79-87.