University of Wisconsin
School of Medicine and Public Health

Publications 2015

January | February | March | April | May | June | July | August | September | October | November | December



  • Nett JE, Andes DR. Antifungal Agents: Spectrum of Activity, Pharmacology, and Clinical Indications. Infect Dis Clin North Am. 2015 Dec 28. pii: S0891-5520(15)00101-4. doi: 10.1016/j.idc.2015.10.012. [Epub ahead of print] Review.

  • Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016 Feb 15;62(4):e1-e50. doi: 10.1093/cid/civ933. Epub 2015 Dec 16.

  • Raman N, Marchillo K, Lee MR, Rodríguez López AL, Andes DR, Palecek SP, Lynn DM. Intraluminal Release of an Antifungal β-Peptide Enhances the Antifungal and Anti-Biofilm Activities of Multilayer-Coated Catheters in a Rat Model of Venous Catheter Infection. ACS Biomater Sci Eng. 2016 Jan 11;2(1):112-121. Epub 2015 Dec 8.

  • Wille CK, Nawandar DM, Henning AN, Ma S, Oetting KM, Lee D, Lambert P, Johannsen EC, Kenney SC. 5-hydroxymethylation of the EBV genome regulates the latent to lytic switch. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7257-65. doi: 10.1073/pnas.1513432112. Epub 2015 Dec 9.

  • Wang A, Welch R, Zhao B, Ta T, Keleş S, Johannsen E. EBNA3 proteins regulate EBNA2 binding to distinct RBPJ genomic sites. J Virol. 2015 Dec 30. pii: JVI.02737-15. [Epub ahead of print]

  • Wang H, Li M, Lerksuthirat T, Klein B, Wüthrich M. The C-type lectin receptor MCL mediates vaccine-induced immunity against infection with Blastomyces dermatitidis. Infect Immun. 2015 Dec 14. pii: IAI.01263-15. [Epub ahead of print]

  • Maki DG. Risk for septic arthritis was increased in adults with incident diagnosis of gout. Ann Intern Med. 2015 Dec 15;163(12):JC12. doi: 10.7326/ACPJC-2015-163-12-012. No abstract available.

  • Becerra BJ, Banta JE, Ghamsary M, Martin LR, Safdar N. Burden of Mental Illness on Hospital and Patient Outcomes among Asthma Hospitalizations. J Asthma. 2015 Dec 14:1-20. [Epub ahead of print]

  • Safdar N, Codispoti N, Purvis S, Knobloch MJ. Patient perspectives on indwelling urinary catheter use in the hospital. Am J Infect Control. 2015 Dec 14. pii: S0196-6553(15)01066-4. doi: 10.1016/j.ajic.2015.10.011. [Epub ahead of print]

  • Aktas B, De Wolfe TJ, Tandee K, Safdar N, Darien BJ, Steele JL. The Effect of Lactobacillus casei 32G on the Mouse Cecum Microbiota and Innate Immune Response Is Dose and Time Dependent. PLoS One. 2015 Dec 29;10(12):e0145784. doi: 10.1371/journal.pone.0145784. eCollection 2015


  • Becerra MB, Becerra BJ, Safdar N. A nationwide assessment of asthma-mental health nexus among veterans.J Asthma. 2015 Nov 7:1-6. [Epub ahead of print]

  • Lepak A, Marchillo K, VanHecker J, Azie N, Andes D. Extended Interval Micafungin Using Humanized PK/PD in Mice. Antimicrob Agents Chemother. 2015 Nov 9. pii: AAC.02124-15. [Epub ahead of print]

  • Walsh TJ, Azie N, Andes DR. Development of New Strategies for Echinocandins: Progress in Translational Research. Clin Infect Dis. 2015 Dec 1;61 Suppl 6:S601-3. doi: 10.1093/cid/civ676.

  • Heath B, Bernhardt J, Michalski TJ, Crnich CJ, Moehring R, Schmader KE, Olds D, Higgins PA, Jump RL. Results of a Veterans Affairs employee education program on antimicrobial stewardship for older adults. Am J Infect Control. 2015 Nov 6. pii: S0196-6553(15)01027-5. doi: 10.1016/j.ajic.2015.09.026. [Epub ahead of print]

  • Buss BA, Schulz LT, Reed KD, Fox BC. MALDI-TOF utility in a region with low antibacterial resistance rates. Clin Infect Dis. 2015 Nov 17. pii: civ962. [Epub ahead of print] No abstract available.

  • Schulte DM, Sethi A, Gangnon R, Duster M, Maki DG, Safdar N. Risk factors for Candida colonization and Co-colonization with multi-drug resistant organisms at admission. Antimicrob Resist Infect Control. 2015 Nov 14;4:46. doi: 10.1186/s13756-015-0089-9. eCollection 2015.

  • O'Neill MB, Mortimer TD, Pepperell CS. Diversity of Mycobacterium tuberculosis across Evolutionary Scales. PLoS Pathog. 2015 Nov 12;11(11):e1005257. doi: 10.1371/journal.ppat.1005257. eCollection 2015 Nov.

  • Braus N, Campbell TC, Kwekkeboom KL, Ferguson S, Harvey C, Krupp AE, Lohmeier T, Repplinger MD, Westergaard RP, Jacobs EA, Roberts KF, Ehlenbach WJ. Prospective study of a proactive palliative care rounding intervention in a medical ICU. Intensive Care Med. 2015 Nov 10. [Epub ahead of print]


  • Sabnis SS, Conway JH. Overcoming Challenges to Childhood Immunizations Status. Pediatr Clin North Am. 2015 Oct;62(5):1093-109. doi: 10.1016/j.pcl.2015.05.004. Epub 2015 Jul 16. Review.

  • Muñoz JF, Gauthier GM, Desjardins CA, Gallo JE, Holder J, Sullivan TD, Marty AJ, Carmen JC, Chen Z, Ding L, Gujja S, Magrini V, Misas E, Mitreva M, Priest M, Saif S, Whiston EA, Young S, Zeng Q, Goldman WE, Mardis ER, Taylor JW, McEwen JG, Clay OK, Klein BS, Cuomo CA. The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia. PLoS Genet. 2015 Oct 6;11(10):e1005493. doi: 10.1371/journal.pgen.1005493. eCollection 2015 Oct.

  • Nawandar DM, Wang A, Makielski K, Lee D, Ma S, Barlow E, Reusch J, Jiang R, Wille CK, Greenspan D, Greenspan JS, Mertz JE, Hutt-Fletcher L, Johannsen EC, Lambert PF, Kenney SC. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells.PLoS Pathog. 2015 Oct 2;11(10):e1005195. doi: 10.1371/journal.ppat.1005195. eCollection 2015 Oct.

  • Sidoryk K, Świtalska M, Jaromin A, Cmoch P, Bujak I, Kaczmarska M, Wietrzyk J, Dominguez EG, Żarnowski R, Andes DR, Bańkowski K, Cybulski M, Kaczmarek Ł. The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents.Eur J Med Chem. 2015 Oct 20;105:208-219. doi: 10.1016/j.ejmech.2015.10.022. [Epub ahead of print]

  • Abad CL, Safdar N. The Reemergence of Measles. Curr Infect Dis Rep. 2015 Dec;17(12):51. doi: 10.1007/s11908-015-0506-5.

  • Jeannina A. Smith, MD, Greg Gauthier, MD.  New Developments in Blastomycosis.  Semin Respir Crit Care Med.  2015 Oct.;36:715-728.  doi: 10.1055/s-0035-1562898. [Epub ahead of print]


  • Smith JA, Gauthier G. New Developments in Blastomycosis. Semin Respir Crit Care Med. 2015 Oct;36(5):715-28. doi: 10.1055/s-0035-1562898. Epub 2015 Sep 23.

  • Barker A, Duster M, Van Hoof S, Safdar N. Nontyphoidal Salmonella: An Occupational Hazard for Clinical Laboratory Workers. Appl Biosaf. 2015;20(2):72-74.

  • Nett JE, Zarnowski R, Cabezas-Olcoz J, Brooks EG, Berhardt J, Marchillo K, Mosher DF, Andes DR. Host contributions to construction of three device-associated Candida biofilms. Infect Immun. 2015 Sep 14. pii: IAI.00931-15. [Epub ahead of print]

  • Crnich CJ, Jump R, Trautner B, Sloane PD, Mody L. Optimizing Antibiotic Stewardship in Nursing Homes: A Narrative Review and Recommendations for Improvement. Drugs Aging. 2015 Sep;32(9):699-716. doi: 10.1007/s40266-015-0292-7.

  • Nanjappa SG, Hernández-Santos N, Galles K, Wüthrich M, Suresh M, Klein BS. Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia. PLoS Pathog. 2015 Sep 14;11(9):e1005161. doi: 10.1371/journal.ppat.1005161.

  • Lepak A, Marchillo K, VanHecker J, Andes D. Impact of Glycopeptide Resistance in Staphylococcus aureus on the Dalbavancin In Vivo Pharmacodynamic Target. Antimicrob Agents Chemother. 2015 Sep 21. pii: AAC.01717-15. [Epub ahead of print]

  • Beaussart A, Brandhorst T, Dufrêne YF, Klein BS. Blastomyces Virulence Adhesin-1 Protein Binding to Glycosaminoglycans Is Enhanced by Protein Disulfide Isomerase. MBio. 2015 Sep 22;6(5). pii: e01403-15. doi: 10.1128/mBio.01403-15.

  • Ackley SF, Liu F, Porco TC, Pepperell CS. Modeling historical tuberculosis epidemics among Canadian First Nations: effects of malnutrition and genetic variation. PeerJ. 2015 Sep 24;3:e1237. doi: 10.7717/peerj.1237. eCollection 2015.

  • Rao K, Safdar N. Fecal microbiota transplantation for the treatment of Clostridium difficile infection. J Hosp Med. 2015 Sep 7. doi: 10.1002/jhm.2449. [Epub ahead of print] Review.

  • Chopra V, Flanders SA, Saint S, Woller SC, O'Grady NP, Safdar N, Trerotola SO, Saran R, Moureau N, Wiseman S, Pittiruti M, Akl EA, Lee AY, Courey A, Swaminathan L, LeDonne J, Becker C, Krein SL, Bernstein SJ. The Michigan Appropriateness Guide for Intravenous Catheters (MAGIC): Results From a Multispecialty Panel Using the RAND/UCLA Appropriateness Method. Ann Intern Med. 2015 Sep 15;163(6 Suppl):S1-S40. doi: 10.7326/M15-0744.

  • Kolehmainen C, Stahr A, Kaatz A, Brennan M, Vogelman B, Cook J, Carnes M. Post-Code PTSD Symptoms in Internal Medicine Residents Who Participate in Cardiopulmonary Resuscitation Events: A Mixed Methods Study. J Grad Med Educ. 2015 Sep;7(3):475-9. doi: 10.4300/JGME-D-14-00424.1.

  • Fu Q, Inankur B, Yin J, Striker R, Lan Q. Sterol Carrier Protein 2, a Critical Host Factor for Dengue Virus Infection, Alters the Cholesterol Distribution in Mosquito Aag2 Cells. J Med Entomol. 2015 Sep;52(5):1124-34. doi: 10.1093/jme/tjv101. Epub 2015 Jul 25.

  • Leonhardt KK, Keuler M, Safdar N, Hunter P. Ebola Preparedness Planning and Collaboration by Two Health Systems in Wisconsin, September to December 2014.Disaster Med Public Health Prep. 2015 Sep 15:1-7. [Epub ahead of print]


  • Lepak AJ, Parhi A, Madison M, Marchillo K, VanHecker J, Andes DR. In vivo Pharmacodynamic Evaluation of an FtsZ Inhibitor, TXA-709 and its Active Metabolite TXA-707, in the Murine Neutropenic Thigh Infection Model. Antimicrob Agents Chemother. 2015 Aug 10. pii: AAC.01464-15.

  • Zhang F, Adnani N, Vazquez-Rivera E, Braun DR, Tonelli M, Andes DR, Bugni TS. Application of 3D NMR for Structure Determination of Peptide Natural Products.J Org Chem. 2015 Aug 14.

  • Verweij PE, Ananda-Rajah M, Andes D, Arendrup MC, Brüggemann RJ, Chowdhary A, Cornely OA, Denning DW, Groll AH, Izumikawa K, Kullberg BJ, Lagrou K, Maertens J, Meis JF, Newton P, Page I, Seyedmousavi S, Sheppard DC, Viscoli C, Warris A, Donnelly JP. International expert opinion on the management of infection caused by azole-resistant Aspergillus fumigatus.  Drug Resist Updat. 2015 Aug 7. pii: S1368-7646(15)00035-7. doi: 10.1016/j.drup.2015.08.001.

JULY 2015

  • Becerra MB, Becerra BJ, Banta JE, Safdar N. Impact of Clostridium difficile infection among pneumonia and urinary tract infection hospitalizations: an analysis of the Nationwide Inpatient Sample. BMC Infect Dis. 2015 Jul 1;15:254. doi: 10.1186/s12879-015-0925-9.

  • Zellmer C, Van Hoof S, Safdar N. Variation in health care worker removal of personal protective equipment. Am J Infect Control. 2015 Jul 1;43(7):750-1. doi: 10.1016/j.ajic.2015.02.005.

  • Koepke R, Kahn D, Petit AB, Schauer SL, Hopfensperger DJ, Conway JH, Davis JP. Pertussis and Influenza Vaccination Among Insured Pregnant Women - Wisconsin, 2013-2014. MMWR Morb Mortal Wkly Rep. 2015 Jul 17;64(27):746-50.

  • Barker A, Duster M, Valentine S, Archbald-Pannone L, Guerrant R, Safdar N.  Probiotics for Clostridium difficile infection in adults (PICO): Study protocol for a double-blind, randomized controlled trial. Contemp Clin Trials. 2015 Jul 22;44:26-32. doi: 10.1016/j.cct.2015.07.015. [Epub ahead of print]

JUNE 2015

  • Safdar N, Odden A, Abad CL, Thapa R, Saint S. Clinical problem-solving: In sight and out of mind. N Engl J Med. 2015 Jun 4;372(23):2218-23. doi: 10.1056/NEJMcps1413402.

  • Davis SA, Vincent BM, Endo MM, Whitesell L, Marchillo K, Andes DR, Lindquist S, Burke MD. Nontoxic antimicrobials that evade drug resistance.Nat Chem Biol. 2015 Jun 1. doi: 10.1038/nchembio.1821.

  • Caya T, Musuuza J, Yanke E, Schmitz M, Anderson B, Carayon P, Safdar N. Using a Systems Engineering Initiative for Patient Safety to Evaluate a Hospital-wide Daily Chlorhexidine Bathing Intervention. J Nurs Care Qual. 2015 Jun 1.

  • Singh N, Winston DJ, Limaye AP, Pelletier S, Safdar N, Morris MI, Meneses K, Busuttil RW, Wagener MM, Wheat LJ. Performance Characteristics of Galactomannan and β-d-Glucan in High-Risk Liver Transplant Recipients Transplantation. 2015 Jun 4.

  • Wampole AJ, Anderson HM, Wald ER. A Case of Postinfectious Protein S Deficiency Masquerading as Henoch-Schönlein Purpura. Clin Pediatr (Phila). 2015 Jun 10. pii: 0009922815590116. [Epub ahead of print]

  • Koepke R, Bartholomew ML, Eickhoff JC, Ayele RA, Rodd D, Kuennen J, Rosekrans J, Warshauer D, Conway JH, Davis JP. Widespread Bordetella parapertussis Infections - Wisconsin, 2011-2012: Clinical and Epidemiologic Features and Antibiotic Use for Treatment and Prevention.  Clin Infect Dis. 2015 Jun 25. pii: civ514. [Epub ahead of print]

  • Mody L, Crnich C. Effects of Excessive Antibiotic Use in Nursing Homes. JAMA Intern Med. 2015 Jun 29. doi: 10.1001/jamainternmed.2015.2774. [Epub ahead of print]

  • Marty AJ, Broman AT, Zarnowski R, Dwyer TG, Bond LM, Lounes-Hadj Sahraoui A, Fontaine J, Ntambi JM, Keleş S, Kendziorski C, Gauthier GM. Fungal Morphology, Iron Homeostasis, and Lipid Metabolism Regulated by a GATA Transcription Factor in Blastomyces dermatitidis. PLoS Pathog. 2015 Jun 26;11(6):e1004959. doi: 10.1371/journal.ppat.1004959. eCollection 2015 Jun.

  • Genz A, Kirk G, Piggott D, Mehta SH, Linas BS, Westergaard RP. Uptake and Acceptability of Information and Communication Technology in a Community-Based Cohort of People Who Inject Drugs: Implications for Mobile Health Interventions. JMIR Mhealth Uhealth. 2015 Jun 25;3(2):e70. doi: 10.2196/mhealth.3437.

  • Barocas JA, Baker L, Hull SJ, Stokes S, Westergaard RP. High uptake of naloxone-based overdose prevention training among previously incarcerated syringe-exchange program participants.Drug Alcohol Depend. 2015 Jun 24. pii: S0376-8716(15)00322-1. doi: 10.1016/j.drugalcdep.2015.06.023. [Epub ahead of print]

  • Nett JE, Andes DR. Fungal Biofilms: In Vivo Models for Discovery of Anti-Biofilm Drugs. Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MB-0008-2014.

MAY 2015

  • Evans CT, Safdar N. Current Trends in the Epidemiology and Outcomes of Clostridium difficile Infection.  Clin Infect Dis. 2015 May 15;60 Suppl 2:S66-71. doi: 10.1093/cid/civ140.

  • van der Linden JW, Arendrup MC, Warris A, Lagrou K, Pelloux H, Hauser PM, Chryssanthou E, Mellado E, Kidd SE, Tortorano AM, Dannaoui E, Gaustad P, Baddley JW, Uekötter A, Lass-Flörl C, Klimko N, Moore CB, Denning DW, Pasqualotto AC, Kibbler C, Arikan-Akdagli S, Andes D, Meletiadis J, Naumiuk L, Nucci M, Melchers WJ, Verweij PE. Prospective Multicenter International Surveillance of Azole Resistance in Aspergillus fumigatus.  Emerg Infect Dis. 2015 Jun;21(6):1041-4. doi: 10.3201/eid2106.140717.

  • Ramanathan S, Hill JN, Cameron KA, Safdar N, Guihan M, Evans CT. Relationship between knowledge and attitudes of methicillin-resistant Staphylococcus aureus and hand hygiene behavior in Veterans with spinal cord injury and disorder. Am J Infect Control. 2015 May 1;43(5):537-9. doi: 10.1016/j.ajic.2015.01.030.

  • Blakney R, Yanke E, Fink C, Wigton R, Safdar N. Optimizing diagnostic testing for Clostridium difficile: The perceptions of physicians and nurses on when to order testing for C difficile. Am J Infect Control. 2015 May 7. pii: S0196-6553(15)00195-9. doi: 10.1016/j.ajic.2015.03.025. [Epub ahead of print]

  • Safdar N, Perencevich E. Crossing the quality chasm for Clostridium difficile infection prevention. BMJ Qual Saf. 2015 May 15. pii: bmjqs-2015-004344. doi: 10.1136/bmjqs-2015-004344. [Epub ahead of print]

  • Morgan DJ, Braun B, Milstone AM, Anderson D, Lautenbach E, Safdar N, Drees M, Meddings J, Linkin DR, Croft LD, Pineles L, Diekema DJ, Harris AD. Lessons learned from hospital ebola preparation. Infect Control Hosp Epidemiol. 2015 Jun;36(6):627-31. doi: 10.1017/ice.2015.61.

APRIL 2015

  • Ohashi M, Holthaus AM, Calderwood MA, Lai CY, Krastins B, Sarracino D, Johannsen E. The EBNA3 Family of Epstein-Barr Virus Nuclear Proteins Associates with the USP46/USP12 Deubiquitination Complexes to Regulate Lymphoblastoid Cell Line Growth.PLoS Pathog. 2015 Apr 9;11(4):e1004822. doi: 10.1371/journal.ppat.1004822. eCollection 2015 Apr.

  • Vergidis P, Avery RK, Joseph Wheat L, Dotson JL, Assi MA, Antoun SA, Hamoud KA, Burdette SD, Freifeld AG, McKinsey DS, Money ME, Myint T, Andes DR, Hoey CA, Kaul DA, Dickter JK, Liebers DE, Miller RA, Muth WE, Prakash V, Steiner FT, Walker RC, Hage CA.Histoplasmosis Complicating Tumor Necrosis Factor-α Blocker Therapy: A Retrospective Analysis of 98 Cases.Clin Infect Dis. 2015 Apr 13. pii: civ299. [Epub ahead of print]

  • Theuretzbacher U, Ambrose PG, MacGowan AP, Andes DR, Sörgel F, Derendorf H, Mouton JW, Drusano GL, Tulkens PM, Dudley MN, Cars O, Nation RL. In memoriam William A. Craig.Antimicrob Agents Chemother. 2015 Apr 20. pii: AAC.00849-15. [Epub ahead of print]

  • Blakney R, Gudnadottir U, Warrack S, O'Horo JC, Anderson M, Sethi A, Schmitz M, Wang J, Duster M, Ide E, Safdar N. The relationship between patient functional status and environmental contamination by Clostridium difficile: a pilot study. Infection. 2015 Apr 14. [Epub ahead of print]

  • Linas BS, Latkin C, Genz A, Westergaard RP, Chang LW, Bollinger RC, Kirk GD. Utilizing mHealth methods to identify patterns of high risk illicit drug use. Drug Alcohol Depend. 2015 Apr 5. pii: S0376-8716(15)00187-8. doi: 10.1016/j.drugalcdep.2015.03.031.

  • McCarty TP, Baddley JW, Walsh TJ, Alexander BD, Kontoyiannis DP, Perl TM, Walker R, Patterson TF, Schuster MG, Lyon GM, Wingard JR, Andes DR, Park BJ, Brandt ME, Pappas PG; TRANSNET Investigators. Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).Med Mycol. 2015 Apr 23. pii: myv018.

  • Carnes M, Vogelman B. Women's Health Fellowships: Examining the Potential Benefits and Harms of Accreditation. J Womens Health (Larchmt). 2015 Apr 28. [Epub ahead of print]

  • Kram JJ, Borlaug G, Safdar N, Sethi A. Development and Distribution of Educational Materials for Carbapenem-Resistant Enterobacteriaceae Among Acute and Long-term Care Facilities. WMJ. 2015 Apr;114(2):48-51.

MARCH 2015