Immunology and Genitourinary Tumor Biology

Douglas McNeel, MD, PhD, is a genitourinary medical oncologist with a clinical and laboratory research focus on the immunotherapy of prostate cancer. 

Portrait of Dr. Doug McNeel

Vaccines for Prostate Cancer Treatment

Dr. McNeel’s lab focuses on prostate cancer immunology.  Using mouse cancer models and blood/tissue samples from patients with prostate cancer, his team studies how vaccines can be used for the treatment of prostate cancer. 

This research has specifically studied the mechanisms of action and resistance to immunization with DNA vaccines, has tested the ability of these vaccines to eliminate prostate cancer cells in laboratory models, and has led to the conduct of several clinical trials with these vaccines.

This work has led to over 100 scientific publications, multiple patents, and a spin-off biotech company.

McNeel Lab Website


Funding Support

The McNeel lab has been continuously funded for over 20 years by the National Institutes of Health, the Department of Defense Prostate Cancer Research Program, and/or the Prostate Cancer Foundation.

Closeup of lab pipettes
Join Us!

The McNeel Lab has open positions for motivated undergraduate and graduate students, as well as postdoctoral fellows interested in translational research focused on the immunotherapy of prostate cancer.

closeup of a male scientist in white lab coat working in the lab

Help Us Transform Medicine

You can help support research by making a gift to the Department of Medicine's Excellence in Hematology/Oncology Fund.