University of Wisconsin
School of Medicine and Public Health

The role of vascular effects on cognition, and Alzheimer's disease biomarkers


Vascular Risk Factors and Cognition Treatments

Dr. Carlsson's research focuses on the effects of vascular risk factors and their treatments on cognition and biomarkers for Alzheimer's disease in persons at risk for dementia. She and her colleagues are conducting clinical trials investigating the impact of vascular risk factors on risk of cognitive decline in middle-aged adults with parental history of Alzheimer's disease; how vascular risk factors are related to biomarkers for Alzheimer's disease found in the blood, cerebrospinal fluid (CSF), and on MRI scans measuring brain blood flow; the relationship between endothelial function and brain blood flow in persons at risk for Alzheimer's disease; and the effects of statins and fish oil on CSF biomarkers, brain blood flow, and cognition in asymptomatic middle-aged adults with parental history of Alzheimer's disease.