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What we published in April 2026
April 30, 2026
Agrawal P, Kumar P, Ali B, Nabeela S, Ikeh MAC, Morschhäuser J, Andes DR, Nobile CJ, Prasad R, Uppuluri P, Panwar SL. Lem3, a phospholipid flippase subunit, influences Candida albicans pathogenicity through maintenance of plasma membrane asymmetry. Microbiol Spectr. 2026:e0296525. Albrecht T, LeCaire TJ, Schroeder M, Stone J, Paniagua U, Peng S, Vidal JL, Houston S, Schrager S, Carlsson CM, Walaszek A. Framing Primary Care Clinicians' Experiences Managing Behavioral and Psychological Symptoms of Dementia: Insights From an Educational Intervention. Wmj. 2026;125(1):210-216. Ali S, Patel AJ, Lehman PC, Fitzjerrells RL, Kasi PM, Mangalam AK. The distinct roles of Negativicoccus and Fusobacterium in proximal- and late-onset colorectal cancer. Gut Microbes. 2026;18(1):2655193. Almasry M, Schell TL, Richard L, Farraye FA, Hayney MS, Caldera F. Influenza vaccine uptake among patients with inflammatory bowel disease: comparable outcomes between telemedicine and in-person care. Crohns Colitis 360. 2026;8(2):otag022. Augustin RC, Wolanskyj-Spinner AP, Rosenstein LJ, Lubner SJ, Halfdanarson TR. Toward Sustainable Hematology/Oncology Fellowship Training Through Career-Aligned Specialization. JCO Oncol Pract. 2026:Op2501343. Aziz F, Famouri L, Thapa B, Singh T, Jewell C, Hayes A, Gaddy A, Rebedew D, Coyle A. Educating the Healers of Tomorrow: Lessons From Innovation, Empathy, and Equity. Wmj. 2026;125(1):4-6,8. Babal JC, Eskola L, Fleming EA, Bade R, Acha-Morfaw M, Eickhoff J, Nelson N. Bearing Witness to Suffering and Social Justice: A Novel Multimodal Medical Humanities Course That Cultivates Compassionate Health Care. Wmj. 2026;125(1):170-173. Balycheva M, Reilly-O'Donnell B, Alvarez-Laviada A, Zhang K, Mazzola M, Sanchez-Alonso JL, Lucarelli C, Medvedev RY, Molina CE, Schobesberger S, Diakonov I, Wright PT, Poulet CE, Bork NI, Trayanova NA, Faggian G, Punjabi P, Nikolaev VO, Glukhov AV, Gorelik J. Downregulation of L-type Ca(2+) current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains. Heart Rhythm. 2026. Bashar SJ, Myhr CB, Titi AH, Zheng Z, Shelef MA. Distinct HLA Associations for Antibody Multireactivity With Citrulline-Containing Type II Collagen Epitopes Versus More Limited Antibody Reactivity With Citrulline-Containing IgG Epitopes in Rheumatoid Arthritis. Arthritis Rheumatol. 2026;78(3):603-612. Bhimanwar RS, Detwiler Z, Zhu JG, Saghafi ST, Winder CA, Davis DB, Mittal A, Sharma V, Harris DA, Chaudhari SN. Rational Design and Evaluation of Novel TGR5 Agonists for Diabetes. Molecules. 2026;31(7). Bruce JY. The role of LGR5 in epithelial cancer. Clin Adv Hematol Oncol. 2026;24(2):102-104. Burton KA, Corbett AM, Antoine A, Stehman C, Keiser EJ, LoConte NK. HSR26-242: Provider Preferences, Perceptions, and Barriers to Colorectal Cancer Screening in Federally Qualified Health Centers. J Natl Compr Canc Netw. 2026;24(3.5). Chari A, Costello C, Krishnan A, Patel K, Banerjee R, Berdeja JG, Biran N, Callander N, Costa LJ, Dhakal B, Gasparetto C, Hansen DK, Kumar A, Nooka AK, Pan D, Richard S. Integrating Recent Evidence and Expert Perspectives Into the Management of Multiple Myeloma: Consensus Recommendations From the 2025 Bridging the Gaps Conference. Am J Hematol. 2026. Che Y, Liu Y, Yao Y, Hill HA, Li Y, Cai Q, Yan F, Jain P, Wang W, Rui L, Wang M. Correction: Exploiting PRMT5 as a target for combination therapy in mantle cell lymphoma characterized by frequent ATM and TP53 mutations. In: Blood Cancer J. Vol 16. United States2026. Claeys KC, Brown CH, Pineles L, Evans CT, Cao L, Trautner BW, Crnich CJ, Balasubramanian P, Ewers T, Gupta K, Strymish JM, Cadena J, O'Neil S, Krein SL, Coffey KC, Morgan DJ. Implementation of Diagnostic Stewardship to Improve Urinary Tract Infection Antibiotic Use Across 3 Medical Centers. Clin Infect Dis. 2026;82(3):494-500. Collij LE, Salvadó G, Horie K, Barthélemy NR, Betthauser TJ, Strandberg O, Smith R, Palmqvist S, Schindler SE, Ossenkoppele R, Janelidze S, Mattsson-Carlgren N, Bateman RJ, Hansson O. Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum. Nat Commun. 2026;17(1). Cullaro G, Im GY, Chandna S, Lee BT, Simonetto DA, Aby ES, Izzy M, Gonzalez SA, Sherman CB, Aron J, Luther J, Goel A, Jophlin LL, Rice J, Chen PH, Asrani S, Lizaola-Mayo B, Elfeki M, Wong F, Biggins SW, Garcia-Tsao G, Singal AK. The management of hepatorenal syndrome-acute kidney injury (HRS-AKI): A national survey of hepatology provider practices. Hepatol Commun. 2026;10(4). Dekan A, Lore S, Yoon YE, Sjöholm A, Tyshkovskiy A, Terskikh A, Cuervo AM, Georgievskaya A, Heinz A, Seluanov A, Adams A, Tsai AP, Murray A, Brunet A, Harten AMV, Spier A, Shenhar B, Pedersen BK, Clasen B, Schumacher B, Kennedy BK, Suetta C, Volbracht C, Kuppe C, Cookson C, Ewald CY, Banila C, Cai D, Valenzano DR, Lamming DW, Rudnic E, Samra EB, Teeling E, Verdin E, Fang EF, Fagagna FDD, Galkin F, Zmudze G, Jasper H, Jang IH, Han JJ, Justice J, Hoeijmakers JHJ, Ramos JMP, Lemaitre JM, Aerssens J, Betts-LaCroix J, Newman JC, Belmonte JCI, Kawamura K, Schaal KM, Egerton K, Abdelmohsen K, Fortney K, Hartenstein L, Niedernhofer L, Katsimpardi L, Melton L, Knudsen LB, Ferrucci L, Sylow L, Demaria M, Schafer MJ, Guasch-Ferré M, Borch-Jensen M, Kholin M, Antonov M, Levitt M, Deleidi M, Merad M, Meldal M, Topors M, Venkatesan M, LeBrasseur NK, Anzinger N, Fedichev P, Kohlhaas P, Mullen PJ, Singhal P, Cabo R, Houtkooper RH, Montgomery R, Smith R, Rosenzweig-Lipson S, Jakimov S, Horvath S, Austad S, Rando TA, White T, Zuber T, Rozmaric T, Wyss-Coray T, Tammela T, Gladyshev VN, Sinatti VVC, Wang W, Harborne W, Liu X, Wang XL, Suh Y, Lee Y, Koch Z, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. Toward actionable interventions in human aging (12th ARDD meeting, 2025). Aging (Albany NY). 2026;18(1):282-302. Dogru RE, Recchia EE, Heninger E, Breneman MT, Maklakova VI, Siraj Z, Kosoff D. Development of a novel fluid removal system to increase throughput and uniformity of fluid exchange in an open microfluidic culture platform. SLAS Technol. 2026;38:100421. Donthineni PR, Shields C, Muralidhar R, Bhatt S, Baer A, Fox R, McCoy SS, Galor A. Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry. Arthritis Care Res (Hoboken). 2026. Eissman JM, Regelson AN, Walters S, Archer DB, Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez J, Kang M, Bush WS, Kunkle BW, Naj AC, Gifford KA, Bilgel M, Kuzma AB, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Vardarajan BN, Mayeux R, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Albert MS, Johnson SC, Engelman CD, Ferrucci L, Bennett DA, Barnes LL, Schneider JA, Resnick SM, Sperling RA, Crane PK, Hohman TJ, Dumitrescu L. Sex-specific genetic drivers of memory, executive functioning and language in older adults. Brain. 2026. Gahvari Z, Callander NS. Autologous Hematopoietic Cell Transplantation (AHCT) for the Treatment of Newly Diagnosed Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2026. Gellner TB, Chen B, Raini SR, Jackson MS, Kraak AK, Petta SC, Paschini M, Schnapp LM, Kim CF, Liu MY. Standardized pipeline for establishing, expanding, and differentiating airway and alveolar organoids from human BAL fluid. Am J Physiol Lung Cell Mol Physiol. 2026. Giarratana AO, Jonaitis E, Przybelski RJ, Cody K, Betthauser TJ, Cadman R, Alberson SF, Christian BT, Johnson SC. Longitudinal Evaluation of (18)F-MK-6240 Along the Alzheimer Disease Continuum. J Nucl Med. 2026. Glawe AJ, Eix EF, Johnson CJ, Zarnowski R, Andes MK, Lazarcik J, Henzler-Wildman KA, Nett JE. Trk1 potassium transport is crucial for effective Candidozyma auris skin colonization. Proc Natl Acad Sci U S A. 2026;123(17):e2602824123. Gray B, Kobayashi S, Bowden JL, Hinman RS, Bennell K, Burgess A, Briggs AM, Duong V, Barton C, French H, Cunningham J, Slater H, O'Brien D, Persaud J, Gallardo N, Allen K, Hamilton DF, Holden MA, Huffman KF, Miller KA, Quicke J, Skou ST, Tan BY, Toomey C, van der Esch M, Hunter DJ, Eyles J. Evaluation of the usability of and engagement with an osteoarthritis e-learning program developed for healthcare professionals. Osteoarthr Cartil Open. 2026;8(2):100787. Greene NK, Seidenberg AB, Butera G, Jesch E, Fakhari H, Wiseman KP, Buykx P, LoConte NK, Scherr CL, Klein WMP. Alcohol and Cancer Messaging: A Scoping Review. Cancer Epidemiol Biomarkers Prev. 2026. Han JH, Jackson JC, Vasilevskis EE, Wang G, Jenkins CA, Duggan MC, Kubilay NZ, Thompson J, Moser KM, Bryant PT, Miller KF, Wrenn JO, Schnelle JF, Dittus RS, Ely EW, Simmons S. The Effect of an Early Cognitive Intervention on Global Cognition in Older Hospitalized Adults With Delirium. J Am Geriatr Soc. 2026. Hegde Y, Caldera F. Letter: Optimising Hepatitis B Vaccination in Inflammatory Bowel Disease - Expanding Strategies Beyond Double-Dose Recombinant Vaccination. Aliment Pharmacol Ther. 2026. Henriquez K, Leja J. Ready for the Aging Population? A Student Perspective Needs Assessment of Geriatric Education Among Graduating Physician Assistant Students. Wmj. 2026;125(1):48-53. Hoeve ESV, Alzoubi B, Rumble ME, Cadmus-Bertram L, Juckett MB, Callander NS, Hematti P, Costanzo ES. A Behavioral Intervention to Improve Symptoms After Hematopoietic Cell Transplantation. J Pain Symptom Manage. 2026. Houghan M, Passini J, Hollnagel F, Zakowski L. Confidence and Efficiency Improvements in Medical Student Notes After Implementation of a Standardized Note Template. Wmj. 2026;125(1):32-35. Joglar JA, Indik JH, Faza NN, Al-Khatib SM, Chugh SS, Cronin E, Daubert JP, Devgun J, Dhande M, Frankel DS, Goldberger ZD, Hurwitz JL, Kusumoto FM, Lakkireddy DR, Makaryus AN, Marine JE, Moore JP, Patton KK, Phoubandith DR, Russo AM, Schreier R, Westerman S. 2026 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology (Revision of the 2015 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology): A Report of the ACC Competency Management Committee. Circ Arrhythm Electrophysiol. 2026:e000094. Kanoria S, Veitch DP, Miller MJ, Aisen PS, Beckett LA, Green RC, Harvey DJ, Jack CR, Jr., Jagust W, Lee EB, Nho K, Nosheny R, Okonkwo OC, Perrin RJ, Petersen RC, Mindt MR, Saykin AJ, Shaw LM, Toga AW, Tosun D, Landau SM, Weiner MW. Clinical impact of the Alzheimer's Disease Neuroimaging Initiative: A review of studies using ADNI data (2023 to June 2025). Alzheimers Dement. 2026;22(4):e71353. Kimura K, Driscoll I, Cook N, Shahzad S, Betthauser TJ, Johnson SC, Asthana S, Gallagher CL, Hermann BP, Sager MA, Blennow K, Zetterberg H, Carlsson CM, Kollmorgen G, Okonkwo OC. Associations between air pollution and markers of neuroinflammation, synaptic dysfunction and core Alzheimer's disease pathology vary by APOE genotype. Neurotox Res. 2026;44(2). Levinson J, Lieber SB, Singh N, Misra D. Reconciling conflicting challenges in older rheumatology patients: remedies from geriatric-rheumatology clinics. In: Ther Adv Musculoskelet Dis. Vol 18. England2026:1759720x261439758. Liu Y, Chen R, Gao X, Zhu F, Ni Q, Bates PD, Wu S, Zai Z, Obernberger VA, Weerawardhene K, Tourdot TK, Petta S, Conyers MJ, Capitini CM, Rui L. PRMT5 inhibition sensitizes B-cell lymphoma cells to ferroptosis. Leukemia. 2026. Massey J, Zarnowski R, Hartman W, Nett JE, Andes DR. In Vivo Characterization of Candida Extracellular Vesicles Reveals Unique Infection Pathway Proteins. JCI Insight. 2026. Matoska T, Findling JW, Wang TS, Evans DB, Dream SY, Javorsky BR, Zwagerman NT, Carroll TB. The Modern Presentation, Etiology, and Rate of Occurrence of Cushing Syndrome Differs when Compared to Prior Population-Based Studies. AACE Endocrinol Diabetes. 2026;13(2):341-346. Page B. Diabetes Spotlight: Dawn Belt Davis, MD, PhD-Strengthening β-Cell Functionality by Identifying Signaling Pathways. Diabetes. 2026;75(4):593-594. Pastorio E, Spillane P, Squires E, Benyahia L, Wilson HK, Swain P, Colosio M, Felles C, Menditto A, Clarke S, Minion B, Pearmain W, Brownstein CG, Porcelli S, Ansdell P. Sex Differences in Durability Following Heavy Intensity Cycling Exercise in Trained Athletes. Scand J Med Sci Sports. 2026;36(4):e70273. Pecanac KE, Golden BP. Reply to Arnold et al.: More Than Words?: Defining Best Practices in Assessing Surrogate Understanding. ATS Sch. 2026. Pewowaruk R, Jaeger BC, Hughes TM, Upadhya B, Kitzman DW, Supiano MA, Gepner AD. Arterial Stiffness Mechanisms and Orthostatic Hypotension in SPRINT: A Randomized Controlled Trial. JACC Adv. 2026;5(5):102734. Pillai P, Akhtar W, Bagwell S, Birkeland LE, Conway JH, DeVoss A, Durkin MS, Evensen MS, Knox K, Hahn T, Hartman J, Hill J, Holt JP, MacMillan K, Rusch R, Salisbury-Afshar E, Seibert C, Sethi AK, Shaw SF, Shrestha S, Timm J, Wenker S, Petty EM, Remington PL, Temte JL. Integrating Medicine and Public Health Through Health Professions Education at a School of Medicine and Public Health. Wmj. 2026;125(1):105-108. Ring S, Bowen AJ, Griffin T, Ferguson JS, Dailey SH. Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis. Laryngoscope. 2026. Rosenfield K, Klok FA, Piazza G, Sharp ASP, F NÁ, Jaff MR, Barco S, Goldhaber SZ, Kucher N, Lang IM, Schmidtmann I, Sterling KM, Araszkiewicz A, Arora V, Cires-Drouet R, Coghlan J, Hobohm L, Ito WD, Jacobson K, Kaiser C, Kopec G, Marx K, McElwee S, Meneveau N, Monteleone P, Montero-Cabezas JM, Olivier CB, Park J, Roik M, Sakhuja R, Tego A, Theurl M, Visveswaran G, Vos JA, Young MN, Asch FM, Konstantinides SV. Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism. N Engl J Med. 2026. Shahid U, Parde N, Smith DL, Dickinson G, Bianco J, Thorpe D, Hota M, Afshar M, Karnik NS, Chhabra N. Development and evaluation of machine learning models for the detection of emergency department patients with opioid misuse from clinical notes. JAMIA Open. 2026;9(2):ooag042. Stahr A, Johnson SK, Adams A, Altschafl B, DeVoss AK, Srinivasan S, Tischendorf J, Zelenksi A, Walaszek A. Educating Health Science Educators: A Flexible, Asynchronous E-Learning Framework for Interprofessional Development in Teaching. Wmj. 2026;125(1):217-220. Stratman Z, MacMillan K, Petty EM, Seibert CS, Hunter P, Crouse B, Lansing K, Foertsch J, Holt J. University of Wisconsin's Outcomes From the Wisconsin Academy for Rural Medicine Track: A Pathway to Rural Primary and Specialty Care. Wmj. 2026;125(1):140-145. Tang Y, Chen Y, Carrillo ND, Cryns VL, Anderson RA, Sun J, Chen M. NRF2 Stabilization by Isoform-Specific Nuclear Phosphoinositides in Stress Response. Oral Sci Homeost Med. 2026. Timsina J, Jiang C, McCartney DL, Tao F, Dalmasso MC, Najar J, Anastasi F, Ohlei O, Puerta Fuentes R, Yang C, Bradley J, Western D, Ali M, Wang C, Wu Y, Liu M, Budde J, Williams J, Mahoney R, Castillo Morales A, Hohman TJ, Dumitrescu L, Wang TC, Tesi N, Kern S, Waern M, Skoog I, van Harten A, Pijnenburg YAL, van der Flier WM, Sánchez-Juan P, Rodriguez-Rodriguez E, Kleineidam L, Peters O, Schneider A, Küçükali F, Bellenguez C, Grenier-Boley B, Heikkinen S, de Rojas I, Rujescu D, Scherbaum N, Hausner L, Düzel E, Grimmer T, Wiltfang J, Vandenberghe R, Engelborghs S, Heilmann-Heimbach S, Schmid M, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Sánchez-Valle R, Álvarez V, García-González P, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Seelaar H, Ramakers I, Papma J, Hulsman M, Laske C, Teipel S, Priller J, Perneczky R, Buerger K, Nöthen MM, Lewczuk P, Kornhuber J, Hampel H, Giegling I, Goldhardt O, Diehl-Schmid J, Andrade V, Heneka MM, Frölich L, Vogelgsang J, Graff C, Thonberg H, Ullgren A, Papenberg G, Deleuze JF, Dufouil C, Wagner M, Jessen F, Holstege H, van Duijn C, Lebouvier T, Hannon O, Leinonen V, Soininen H, Herukka SK, Giedraitis V, Löwenmark M, Kilander L, Genius P, Rodríguez B, Luckett ES, Navarro A, Cano A, Marquié M, Blennow K, Zetterberg H, Lleo A, Boada M, Ruiz A, Lee VM, Van Deerlin VM, Deming Y, Johnson SC, Engelman CD, Pastor P, Alvarez I, Peskind ER, Heslegrave AJ, Saykin AJ, Nho K, Schindler SE, Morris JC, Holtzman DM, McDade E, Renton AE, Goate A, Ibanez L, Riemenschneider M, Albert MS, Laws SM, Porter T, O'Brien EK, Shaw LM, Tijms BM, Ingelsson M, Visser PJ, Hiltunen M, Sleegers K, Ritchie CW, Sims R, Belloy M, Lambert JC, Vilor-Tejedor N, Fernández MV, Li QS, Nagle MW, Marioni RE, Ramirez A, Bertram L, van der Lee SJ, Cruchaga C. GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy. Nat Commun. 2026. Tischendorf J, Sharkey C, Westmas K, Zelenksi AB, Hollnagel F, Chapman E. Three-Year Outcomes of a Longitudinal Department of Medicine Fellow as Medical Educator Training Program Pilot. Wmj. 2026;125(1):221-224. Tun AM, Patel R, St-Pierre F, Ouchveridze J, Niu A, Thordardottir T, Obasi J, Rosenthal A, Pophali PA, Fenske T, Karmali R, Johnston PB, Ahmed S. Neurotoxicity in Older Patients with Relapsed or Refractory Large B-Cell Lymphoma Treated with Chimeric Antigen Receptor T-Cell Therapy: A Multicenter Study. Transplant Cell Ther. 2026. van Rosendael A, Nakanishi R, Bax JJ, Pontone G, Mushtaq S, Buechel RR, Gräni C, Feuchtner G, Lacaita PG, Patel AR, Singulane CC, Choi AD, Al-Mallah M, Andreini D, Karlsberg RP, Cho GW, Rochitte CE, Alasnag M, Hamdan A, Cademartiri F, Maffei E, Marques H, de Araújo Gonçalves P, Gupta H, Hadamitzky M, Khalique O, Kalra D, Mills JD, Nurmohamed NS, Knaapen P, Budoff M, Shaikh K, Martin E, German DM, Ferencik M, Oehler AC, Deaño R, Nagpal P, van Assen M, De Cecco CN, Kamperidis V, Foldyna B, Brendel JM, Cheng VY, Branch KR, Bittencourt M, Bhatti S, Polsani V, Wesbey G, Cardoso R, Blankstein R, Delago A, Pursnani A, Alsaid A, Bloom S, Aquino M, Danad I. AI-Driven Quantitative Coronary CT Angiography in Suspected Coronary Artery Disease: Multicenter CONFIRM2 Registry. JACC Adv. 2026;5(3):102618. Vande Hey JM, Ward D, Buys A, Caldera F, Hayney MS. Hepatitis B challenge dose in vaccinated healthcare personnel susceptible at hire. Vaccine. 2026;82:128589. Wainberg ZA, Manji GA, Bahary N, Ulahannan SV, Pant S, Spigel DR, Uboha NV, Oberstein PE, Saeed A, Beagle B, Kim JY, Wang N, Weeder B, Shitole S, Mrouj K, Scott JR, Ensign LG, DiRenzo DM, Walters MJ, Wu W, Kaplan A, Cho S, Kabbarah O, O'Reilly EM. Quemliclustat and chemotherapy with or without zimberelimab in metastatic pancreatic adenocarcinoma: a randomized phase 1 trial. Nat Med. 2026;32(4):1267-1277. Wrucke DJ, Colosio M, James JJ, Hunter SK, Sundberg CW. Initial contractions of a single-load fatiguing exercise provide a valid assessment of age-related differences in peak power. J Appl Physiol (1985). 2026. Yeware A, Brown C, Chang CC, Pennati A, Galipeau J. Extracellular vesicles mediate intercellular transfer of PD-L1 and bystander T-cell suppression. Cell Mol Life Sci. 2026. Zakowski LJ, Zelenski A, Stahr A. 'How Do I Get There From Here?' Discerning Pathways for Successful Faculty Promotion in Education at a Medical School. Wmj. 2026;125(1):184-187.