University of Wisconsin
School of Medicine and Public Health

Mathur Research

Sameer Mathur, MD, PhD | Eosinophil Biology 

Sameer Mathur, MD, PhD, is a physician-scientist and a practicing allergist-immunologist. His research investigates how eosinophils contribute to disease activity in the context of asthma and eosinophilic esophagitis.

Dr. Sameer Mathur's Faculty Biography

Image
color illustration of eosinophil

The Role of Eosinophils in Airway Inflammation

Dr. Mathur’s research focuses on the role of eosinophils in airway inflammation and inflammatory mechanisms and biomarkers in eosinophilic esophagitis. He also leads clinic-based projects to improve the care for patients with mast cell disorders, including urticarial, angioedema, and mast cell activation syndrome.

Eosinophil illustration: Blausen Medical, CC BY-SA 4.0, via Wikimedia Commons

Research Team

Research Specialist

Active Projects

Eosinophilic Esophagitis  

Our previous work has identified an eosinophil surface marker, CD41, that correlates with changes in esophageal eosinophil counts. We are proceeding with clinical trials to examine its utility as a biomarker for EOE disease activity.

In addition, we have preliminary data recognizing that esophageal epithelium can be infected by respiratory viruses, which suggests that viral infections may contribute to the esophageal inflammatory process. 

Role of Eosinophils in Asthma 

Our group has collaborated with investigators in our division to examine the functional role of eosinophils in asthma.

Electronic Medical Record Analyses of Allergic Diseases 

Our group has worked with residents to explore clinical questions on chronic urticaria, mast cell activation syndrome, and severe asthma. We have used the electronic medical record to generate data to address these questions.

Positions Available

If you are interested in joining our research group, please send a CV and brief description of your research experience and interests to Dr. Mathur at skmathur@wisc.edu

Funding Support

Dr. Mathur's research is funded by the National Institutes of Health and the Department of Medicine Research Committee.

Make a Gift

Help support research by making a gift to the Department of Medicine's Allergy and Immunology Research and Education Fund.