Asthma/COPD & Obstructive Sleep Apnea Study: Call for Participants

Researchers in the UW Department of Medicine are conducting a study to examine whether a common medication used to treat asthma and chronic obstructive pulmonary disease (COPD), inhaled fluticasone, has an effect on risk for sleep apnea. Sleep apnea is when someone stops breathing repeatedly for short periods of time during sleep. An earlier study by UW researchers suggested that inhaled corticosteroids such as fluticasone may increase the risk for sleep apnea in certain individuals. This study will continue to examine the effect of inhaled fluticasone on upper airway collapsibility (floppiness) and may help researchers to understand how and why this occurs.

Male & female volunteers with asthma or COPD who are 18 years or older and who are not currently being treated for sleep apnea are invited to participate.  Persons who use inhaled corticosteroids or who currently smoke will be ineligible for participation. Both U.S. military veterans and non-veterans are invited to participate; however, veterans will be given priority status.

The study will look at two different doses of inhaled fluticasone and will involve nine study visits over 28 weeks for lung function testing, sleep studies, and two magnetic resonance imaging studies (MRIs). Participants will be paid up to $600 for completing the study. The study is being conducted at the William S. Middleton Memorial Veterans Hospital in Madison.

To volunteer for this study or for more information, please contact the Principal Investigator Dr. Mihaela Teodorescu or her study coordinators, Tricia Denman or Diane DeMonaco, at (608) 256-1901 extension 11902, or by email at sleeppulmonaryresearch@medicine.wisc.edu

The University of Wisconsin-Madison allows researchers to use email to send its faculty, staff, and student’s information about research opportunities as part of its research mission. Use of these email addresses has been approved by the campus data custodian (Registrar's Office for students and Budget Planning & Analysis for faculty/staff). The content of this email message has been approved by a University of Wisconsin-Madison Institutional Review Board (IRB). IRBs are charged with protecting the rights and welfare of people who take part in research studies.