Timothy Baker, PhD, emeritus professor, General Internal Medicine and research director, UW Center for Tobacco Research and Intervention, and James Stein, MD (pictured at lower right), professor, Cardiovascular Medicine, have been awarded $1.8M over 4 years (R01 award) from the National Institutes of Health-National Heart, Lung, and Blood Institute for a proposal entitled, "E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease Risk."
Researchers are conducting a clinical study designed to relate the acute and long-term use of e-cigarettes and conventional cigarettes to well-validated cardiovascular and pulmonary disease biomarkers.
A total of 440 volunteers will participate in the study, which involves equally sized groups of people who smoke cigarettes exclusively, people who only use e-cigarettes, people who both smoke and vape, and people who do not use either category of nicotine-containing product.
Data on cardiovascular function, pulmonary function, inflammation, oxidative stress, and other key outcomes will be measured and compared between groups.
"These data will serve as a foundation for future longitudinal investigations of E-cig health effects and will inform public policy decisions, clinical interventions, and patient guidance regarding E-cigarettes," write the researchers.
Dr. Stein is the Robert Turell Professor of Cardiovascular Research.
Photo (top): Person using an e-cigarette, CC-BY-2.0 courtesy of TBEC Review.