Contact Information
Biography
Dr. Johnson is a clinical neuropsychologist with research interests in brain function in Alzheimers Disease and related disorders. Current projects focus on A) the neurobiological and psychological processes that affect memory; B) early detection of Alzheimers Disease with multi-modal imaging including amyloid imaging; C) machine learning based multi-modal imaging markers of AD; D) enriching clinical trials and improving trial design with multi-kernel machine learning to speed the discovery of effective treatments for AD.
Professor in the Dept of Medicine, Section of Geriatrics and Gerontology and affiliated with the following departments and centers on campus at the University of Wisconsin-Madison
Geriatric Research Education and Clinical Center (GRECC), Wm. S. Middleton Memorial Veterans Hospital
Wisconsin Alzheimer’s Disease Research Center
Wisconsin Alzheimer’s Institute
Wisconsin Institute on Aging
Neuroscience Training Program
Department of Psychology
Search for Sterling Johnson's literature abstracts on PubMed
Representative Publications:
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Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation
February 20, 2014
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Extracting and summarizing white matter hyperintensities using supervised segmentation methods in Alzheimer’s disease risk and aging studies
February 7, 2014
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Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer’s disease
January 21, 2014
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Associations between white matter microstructure and amyloid burden in preclinical Alzheimer’s disease: A multimodal imaging investigation
January 1, 2014
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Multi-resolutional Shape Features via Non-Euclidean Wavelets: Applications to Statistical Analysis of Cortical Thickness
January 1, 2014
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Speeding up Permutation Testing in Neuroimaging
December 1, 2013
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Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function
October 19, 2013
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Amyloid burden and neural function in people at risk for AD
September 19, 2013
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Emergence of Mild Cognitive Impairment in Late-Middle-Aged Adults in the Wisconsin Registry for Alzheimer’s Prevention Study
September 13, 2013
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Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study
May 1, 2013
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Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults
April 3, 2013
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White matter microstructural integrity and executive function in Parkinson’s disease
March 19, 2013
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Interleukin-8 and interleukin-10, brain volume and microstructure, and the influence of calorie restriction in old rhesus macaques
March 6, 2013
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Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults
February 1, 2013
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Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer’s disease
January 1, 2013
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Low cerebral blood flow is associated with lower memory function in metabolic syndrome.
January 1, 2013
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Q-MKL: Matrix-induced Regularization in Multi-Kernel Learning with Applications to Neuroimaging
December 3, 2012
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Wavelet based multi-scale shape features on arbitrary surfaces for cortical thickness discrimination
December 1, 2012
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Brain volumetric and microstructural correlates of executive and motor performance in aged rhesus monkeys
November 8, 2012
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Longitudinal volumetric changes following traumatic brain injury: A tensor based morphometry study
November 1, 2012
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Effects of Atorvastatin on Cerebral Blood Flow in Middle-Aged Adults at Risk for Alzheimer's Disease: A Pilot Study
October 1, 2012
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Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients
May 20, 2012
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Calorie restriction reduces the influence of glucoregulatory dysfunction on regional brain volume in aged rhesus monkeys
May 6, 2012
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Head size may modify the impact of white matter lesions on dementia
May 1, 2012
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A generalized form of context-dependent psychophysiological interactions (gPPI): A comparison to standard approaches
April 1, 2012
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Family history of Alzheimer disease predicts hippocampal atrophy in healthy middle-aged adults
February 1, 2012
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MKL-Based Sample Enrichment and Customized Outcomes Enable Smaller AD Clinical Trials
January 1, 2012
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Medial Prefrontal Functional Connectivity - Relation to Memory Self-appraisal Accuracy in Older Adults with and without Memory Disorders
January 1, 2012
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The Effects of Ramipril in Individuals at Risk for Alzheimer's Disease: Results of a Pilot Clinical Trial
January 1, 2012
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Topology based Kernels with Application to Inference Problems in Alzheimer’s disease
October 1, 2011
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A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease
September 1, 2011
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A within-subject comparison of 6-[18F]fluoro-m-tyrosine and 6-[18F]fluoro-L-dopa in Parkinson's disease
September 1, 2011
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Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys
July 1, 2011
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Rate of 6-[18F]fluoro-L-dopa uptake decline in striatal subregions in Parkinson’s disease
March 26, 2011
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Predictive Markers for AD in a Multi-Modality Framework: An Analysis of MCI Progression in the ADNI Population
March 15, 2011
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The Effect of TOMM40 Poly-T length on Gray Matter Volume and Cognition in Middle-Aged Persons with APOE ε3/ε3 Genotype
March 1, 2011
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Effects of Hypoperfusion in Alzheimer's Disease
January 1, 2011
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Effects of Hypoperfusion in Alzheimer's Disease
January 1, 2011
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Functional Magnetic Resonance Imaging of Swallowing: From Neurophysiology to Neuroplasticity
January 1, 2011
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Mapping the structural brain changes in Alzheimer's disease: the independent contribution of two imaging modalities
January 1, 2011
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Swallowing Intentional off-state in aging and Alzheimer’s Disease: A preliminary study
January 1, 2011
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NSAIDs may protect against age-related brain atrophy
September 3, 2010
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White matter is altered with parental family history of Alzheimer’s disease
September 1, 2010
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Homocysteine, neural atrophy, and the effect of caloric restriction in rhesus monkeys
August 4, 2010
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Low HDL cholesterol is associated with lower gray matter volume in cognitively healthy adults
July 15, 2010
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Age-related changes in neural volume and microstructure associated with interleukin-6 are ameliorated by a calorie-restricted diet in old rhesus monkeys
July 1, 2010
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Effects of aging and calorie restriction on white matter in rhesus macaques.
June 10, 2010
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A Calorie-Restricted Diet Decreases Brain Iron Accumulation and Preserves Motor Performance in Old Rhesus Monkeys
June 9, 2010
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White Matter in Aging and Cognition: A Cross-sectional Study of Microstructure in Adults Aged Eighteen to Eighty-Three
May 1, 2010
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Reliability and Precision of Pseudo-continuous Arterial Spin Labeling Perfusion MRI on 3.0 T and Comparison with 15O-water PET in Elderly Subjects at Risk for Alzheimer’s Disease
April 1, 2010
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Rhesus Macaque Brain Morphometry: A Methodological Comparison of Voxel-Wise Approaches
March 1, 2010
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Microstructural diffusion changes are independent of macrostructural volume loss in moderate to severe Alzheimer’s disease
January 1, 2010
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Awareness of memory abilities in community-dwelling older adults with suspected dementia and mild cognitive impairment
January 1, 2010
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Midlife predictors of Alzheimer's disease
December 29, 2009
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Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
July 10, 2009
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Spatially augmented LPboosting for AD classification with evaluations on the ADNI dataset
May 27, 2009
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Posterior Cingulate and Lateral Parietal Gray Matter Volume in Older Adults with Depressive Symptoms
April 15, 2009
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A population-average MRI-based atlas collection of the rhesus macaque
March 1, 2009
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Neurophysiology of swallowing: effects of age and bolus type
February 1, 2009
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The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory
February 1, 2009
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A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women
January 1, 2009
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Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imaging
August 15, 2008
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Effect of parental family history of Alzheimer's disease on serial position profiles
July 1, 2008
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Atorvastatin Therapy is Associated with Greater and Faster Cerebral Hemodynamic Response
June 1, 2008
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Magnetic resonance imaging characterization of brain structure and function in mild cognitive impairment: a review
May 1, 2008
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Hippocampal volume change in the Alzheimer Disease Cholesterol-Lowering Treatment trial
March 1, 2008
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Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease
March 1, 2008
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Associative learning over trials activates the hippocampus in healthy elderly but not mild cognitive impairment
March 1, 2008
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fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's disease
December 17, 2007
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Brain mapping in cognitive disorders: a multidisciplinary approach to learning the tools and applications of functional neuroimaging
October 22, 2007
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Effect of Alzheimer disease risk on brain function during self-appraisal in healthy middle-aged adults
October 1, 2007
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Longitudinal changes in global brain volume between 79 and 409 days after traumatic brain injury: relationship with duration of coma
May 1, 2007
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Anosognosia in mild cognitive impairment: Relationship to activation of cortical midline structures involved in self-appraisal
May 1, 2007
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The Relationship Between Gray Matter Morphometry and Neuropsychological Performance in a Large Sample of Cognitively Healthy Adults.
January 1, 2007
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Relevance to self: A brief review and framework of neural systems underlying appraisal
January 1, 2007
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Hormone effects on fMRI and cognitive measures of encoding: importance of hormone preparation
December 12, 2006
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Neural correlates of self-evaluative accuracy after traumatic brain injury
September 8, 2006
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Network analysis of single-subject fMRI during a finger opposition task
August 1, 2006
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Relationship of cognitive measures and gray and white matter in Alzheimer's disease
August 1, 2006
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Computational models of the hippocampal region: implications for prediction of risk for Alzheimer's disease in non-demented elderly
July 1, 2006
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The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation
May 31, 2006
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Self-appraisal decisions evoke dissociated dorsal-ventral aMPFC networks
April 15, 2006
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Application of Brodmann's area templates for ROI selection in white matter tractography studies
February 1, 2006
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Task-dependent posterior cingulate activation in mild cognitive impairment
January 15, 2006
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Reduced hippocampal activation during episodic encoding in middle-aged individuals at genetic risk of Alzheimer's disease: a cross-sectional study
January 13, 2006
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Structural MRI discriminates individuals with Mild Cognitive Impairment from age-matched controls: A combined neuropsychological and voxel based morphometry study.
January 1, 2006
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The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study
December 2, 2005
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The cerebral response during subjective choice with and without self-reference
December 1, 2005
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Functional MRI neuroanatomic correlates of the Hooper Visual Organization Test
November 1, 2004
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Voxel-based morphometry of unilateral temporal lobe epilepsy reveals abnormalities in cerebral white matter
September 1, 2004
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Metacognitive evaluation, self-relevance, and the right prefrontal cortex
June 1, 2004
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Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment
January 1, 2004
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Functional MRI and Wada determination of language lateralization: a case of crossed dominance
January 1, 2004
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Apolipoprotein E epsilon 4 affects new learning in cognitively normal individuals at risk for Alzheimer's disease
November 1, 2003
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Neural correlates of self-reflection
August 1, 2002
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