1550 LINDEN DR
MADISON, WI 53706-1521
Dr Striker received his MD and PhD from Washington University in St. Louis, Missouri, where he did his thesis work with Dr Scott Hultgren on understanding and blocking the critical P pili attachment factors needed for most urinary tract infections. He did his internal medicine residency in San Francisco just as combination antiretroviral therapy were finally turning the tide against the HIV epidemic. Following his Infectious Disease fellowship and Howard Hughes-supported postdoctoral work with Dr. Karla Kirkegaard at Stanford University on Hepatitis C Virus, he came to the University of Wisconsin. His initial work at UW-Madison focused on improving antiviral therapy including access for Hepatitis C virus, and specifically the role of phosphorylation in flaviviral life cycles, including showing that phosphorylation events contribute to mosquito mediated spread of Dengue and other flaviviruses. He continues to see patients as well as to combine clinical insights with wet bench experiments to improve the treatment of infectious diseases. In recent years, he has focused on developing kinase inhibitors for both viral and bacterial infections, particularly PASTA kinase inhibitors that can sensitize gram positive infections to beta lactam antibiotics as well as efforts to quantify and shrink the HIV reservoir as a means of lessening immune dysfunction that accompanies HIV infection. Dr. Striker's research has been supported by funding from the National Institutes of Health, the American Cancer Society, the Hartwell Foundation, the Wisconsin Partnership Program, the UW Institute for Clinical and Translational Research, and the Veteran’s Association.
Search for Robert Striker's literature abstracts on PubMed