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Craig January is a graduate of the MD-PhD program at the University of Iowa, where he received his medical degree in 1976 and a doctorate in Physiology and Biophysics in 1978. He completed his internship, residency and cardiology fellowship training at the University of Chicago. Dr. January remained at the University of Chicago as an instructor in Medicine, then as an assistant and as an associate professor from 1982 to 1994. He joined the faculty of the University of Wisconsin-Madison Department of Medicine, Division of Cardiovascular Medicine in 1995 (serving as division head from 1995 to 1997 and vice chair of research for the Department of Medicine from 2006-2015).
Dr. January is a clinician-scientist whose research has focused on understanding basic mechanisms of cardiac arrhythmias. In his career, he has studied several ion channels including Na+, L- and T-type Ca++ and K+, and processes involved in the regulation of cardiac contractility. His pioneering research demonstrated an essential role of the L-type Ca++ channel and its 'window current' in generating early afterdepolarizations, a trigger for potentially lethal cardiac arrhythmias. Dr. January's recent research focuses on the molecular mechanisms of the acquired and congenital long QT syndrome. In particular, his lab has been instrumental in defining how mutations in the K+ channel gene, HERG, lead to the congenital long QT syndrome (LQT2). His work has defined abnormalities in protein trafficking as the central mechanism for HERG mutations, which leads to the long QT syndrome.
Dr. January is a Fellow of the American College of Cardiology, and member of several societies including the American Heart Association Basic Sciences Council, Cardiac Electrophysiology Society, Central Society for Clinical Research, Biophysical Society, and North American Society of Pacing and Electrophysiology (now Heart Rhythm Society). He is a past-president of the Cardiac Electrophysiology Society. He has served extensively on peer-review panels including National Institutes of Health Cardiovascular Study Sections (CVA, CVB, clinical trials, K99/R00), national American Heart Association review sections, and VA merit review panels. Dr. January teaches in both clinical and basic settings. Nationally and internationally he has participated as a lecturer in many courses and invited seminars. His teaching accomplishments are well-recognized. Dr. January has been involved in various forms of service including serving as the writing chair for the ACC/AHA/HRS Atrial Fibrillation Guidelines.
Search for Craig January's literature abstracts on PubMed