Nationally Recognized Expertise

The University of Wisconsin Asthma, Allergy, and Pulmonary Research team is nationally known. We have studied asthma for over 30 years and have conducted over 400 research studies with children and adults—work that helps develop new asthma medications and treatment guidelines.

To learn more about participating in a clinical trial, call us at 608-263-0524 or fill out our study intake form.

Dr. Ravi Viswanathan administers a skin test in the clinic

Children's Studies

Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness Study (ORBEX) - 5 to 16 Months Old

A research study in which infants (5 to 16 month olds) with a history of eczema or a parent with physician-diagnosed asthma are given a daily capsule of the investigational medication Broncho-Vaxom® (a mixture of bacteria products) to see if it helps prevent development of wheezing illness or asthma.

Current Studies:

Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness Study (ORBEX)

For more information, please contact us at pediatricasthma@medicine.wisc.edu, or call us at (608) 263-3360 or toll free (866) WIS-CARE.

Or contact us via our online webform

Inner City Asthma Consortium (ICAC)

In 2002, the National Institutes of Health-National Institute of Allergy and Infectious Diseases (NIAID) created the Inner City Asthma Consortium (ICAC). ICAC is a multi-study, multi-center initiative to study the causes of the urban asthma epidemic that afflicts millions of children and to develop treatments to improve control of asthma in this population and for children in general. UW-Madison currently provides scientific direction and overall ICAC management services. UW-Madison staff in the Departments of Medicine and Pediatrics deliver technical support involving pulmonary function testing, laboratory sample processing, contracting, procurement and budgetary matters. ICAC is composed of the UW-Madison based Administrative Center, eleven clinical sites located in major U.S. cities, four basic science laboratories, including one at the UW-Madison, and a Statistical and Clinical Coordinating Center.

Find out more on the ICAC web page

For more information, please contact us at khernand@medicine.wisc.edu.

PrecISE: Precision Interventions for Severe and/or Exacerbation-Prone Asthma

PrecISE, the Precision Interventions for Severe and/or Exacerbation-Prone Asthma Network, is a research study to understand how to treat different types of severe asthma. This study is currently recruiting people age 12 or older who experience asthma attacks or frequent asthma symptoms. Participants in the study will receive one or more study medicines for their severe asthma, in addition to their regularly prescribed asthma controller medication(s). Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.

This study is sponsored by the U.S. National Heart, Lung, and Blood Institute (NHLBI). For more information about PrecISE or to see if you qualify, call us at 608-263-0524, email us at pulm-research@medicine.wisc.edu or fill out this questionnaire.

Find out more on the PreCISE study web page

CANOE: Childhood Allergy and the NeOnatal Environment

The goal of CANOE is to determine how early-life environmental factors cause childhood asthma and allergies. Previous birth cohort studies have found that early-life environmental factors, such as allergies, pollutants, viruses and bacteria, contribute to the development of asthma and allergies. We are doing this research because there continues to be a strong need to understand the causes of asthma and allergies.

Find out more on the CANOE study web page

For more information, please contact us at canoe@medicine.wisc.edu

SUNBEAM: Systems Biology of Early Atopy

The goal of the SUNBEAM study is to learn more about factors that put very young children at higher risk for food allergies and eczema. This study will focus on risk factors that may be present before, during, and after birth and through the age of 3 years.

Find out more on the SUNBEAM study web page

For more information, please contact us at sunbeam@medicine.wisc.edu

ECHO: Environmental influences on Child Health Outcomes

The goal of the ECHO study is to understand the effects of a broad range of early environmental influences on child health and development. ECHO is dedicated to both learning what factors affect child health and to finding ways to enhance it. The ECHO Program studies five areas of health: pre-, peri- and postnatal (pregnancy and birth), upper and lower airway (breathing), obesity (body weight), neurodevelopment (brain development) and positive health (well-being).

Find out more on the ECHO study web page

For more information, please contact us at ECHO@medicine.wisc.edu

MARI: Microbes and Respiratory Illnesses

Childhood allergies and asthma are becoming more common worldwide. The MARI study, which stands for Microbes and Respiratory Illnesses, is looking at how environmental factors like living on farms or in cities impact children's health. Our research aims to understand why some kids are less likely to develop allergies and respiratory illnesses.

Find out more on the MARI study web page

For more information, please contact maristudy@show.wisc.edu.

Adult Studies

PrecISE: Precision Interventions for Severe and/or Exacerbation-Prone Asthma

PrecISE, the Precision Interventions for Severe and/or Exacerbation-Prone Asthma Network, is a research study to understand how to treat different types of severe asthma. This study is currently recruiting people age 12 or older who experience asthma attacks or frequent asthma symptoms. Participants in the study will receive one or more study medicines for their severe asthma, in addition to their regularly prescribed asthma controller medication(s). Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.

This study is sponsored by the U.S. National Heart, Lung, and Blood Institute (NHLBI). For more information about PrecISE or to see if you qualify, call us at 608-263-0524, email us at pulm-research@medicine.wisc.edu, or or fill out this questionnaire.

Find out more on the PreCISE study web page

Pulmonary and Asthma Research PPG Blood Draw Study

Function of the Isolated Eosinophil in Asthma

The purpose of this study is to study how eosinophils contribute to airway irritation and changes in asthma.

For more information, please see the PreCISE study adolescent consent form.

If you are interested in this study, please contact us:

Severe Asthma Research Program (SARP)

The Severe Asthma Research Program (SARP) is an observational study looking to improve the understanding and development of better treatments for severe asthmatics. This study is enrolling both participants who have asthma, and those who do not have asthma. Study participation involves between 4 and 5 clinic visits over three years and 3 phone calls. Compensation up to $585 is provided.

This study is sponsored by the U.S. National Institutes of Health (NIH). For more information about PrecISE or to see if you qualify, call us at 608-263-0524 or email us at pulm-research@medicine.wisc.edu.

For more information, please see the SARP consent form or fill out this questionnaire.

PROTECT Peanut Allergy Study

We are looking at an investigational medication to see how safe and well-tolerated it is in peanut-allergic adults.

You may be able to take part in this study if you:

  • are 18 – 50 years old 
  • have a physician-diagnosed peanut allergy with a history of reactions after eating peanuts  

The study will last for up to 5 weeks and will require up to 3 visits at the UW Hospital and Clinics Asthma & Allergy Research Unit. All study-related care will be provided at no cost and you may be compensated up to $475 for your time and participation. 

If you would like to learn more about the study, please contact pulm-research@medicine.wisc.edu or call 608-263-0524.

Study flier (PDF)

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Find Out More

Contact us directly at 608-263-0524 or fill out our study intake form.

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